|
ovarian neoplasm
|
0.070 |
GeneticVariation
|
disease |
LHGDN |
We used a genetic association study design to determine if common genetic variation (frequency > or = 5%) in EMSY was associated with breast or ovarian cancer risk in the British population.
|
16029503 |
2005 |
|
Carcinoma of Male Breast
|
0.010 |
Biomarker
|
disease |
BEFREE |
We reported EMSY amplification in 34.7 % of MBCs.
|
27628328 |
2016 |
|
Malignant neoplasm of male breast
|
0.010 |
Biomarker
|
disease |
BEFREE |
We reported EMSY amplification in 34.7 % of MBCs.
|
27628328 |
2016 |
|
Mammary Neoplasms
|
0.320 |
GeneticVariation
|
group |
BEFREE |
We hypothesized that breast tumors from BRCA2 mutation carriers would be less likely than other familial breast cancers to exhibit EMSY amplification.
|
21327470 |
2011 |
|
pricking of skin
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
We found that the 10 loci associate with sensitization to different allergens in a nonspecific manner and that one in particular, C11orf30-rs2155219, doubles the risk of poly-sensitization (specific IgE/4 allergens: OR = 1.81, 95% CI 0.80-4.24; skin prick test/4+ allergens: OR = 2.27, 95% CI 1.34-3.95).
|
25546184 |
2015 |
|
IgE-mediated food allergy
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
We found FLG, HLA, IL10, IL13, as well as some evidence for other variants (SPINK5, SERPINB and C11orf30) that are associated with food allergy.
|
30835860 |
2019 |
|
Malignant neoplasm of ovary
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We found no association between common genetic variation in EMSY and risk of breast or ovarian cancer in two large study sets of white British women.
|
16029503 |
2005 |
|
Carcinoma, Ovarian Epithelial
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
We found no association between common genetic variation in EMSY and risk of breast or ovarian cancer in two large study sets of white British women.
|
16029503 |
2005 |
|
ovarian neoplasm
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
We found no association between common genetic variation in EMSY and risk of breast or ovarian cancer in two large study sets of white British women.
|
16029503 |
2005 |
|
Papillary thyroid carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
We conclude that 11q13.5-q14 is not imbalanced in PTC, but there is evidence suggesting that EMSY might be of relevance in PTC etiology.
|
18787380 |
2008 |
|
Malignant neoplasm of ovary
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We analysed the role of germline EMSY variation in breast/ovarian cancer predisposition.
|
28738860 |
2017 |
|
Carcinoma, Ovarian Epithelial
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
We analysed the role of germline EMSY variation in breast/ovarian cancer predisposition.
|
28738860 |
2017 |
|
ovarian neoplasm
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
We analysed the role of germline EMSY variation in breast/ovarian cancer predisposition.
|
28738860 |
2017 |
|
Dermatitis, Atopic
|
0.330 |
Biomarker
|
disease |
CTD_human |
We also replicated the associations of the FLG, C11orf30, TMEM232-SLC25A46, TNFRSF6B-ZGPAT, OVOL1, ACTL9 and KIF3A-IL13 loci that were previously reported in GWAS of European and Chinese individuals and a meta-analysis of GWAS for atopic dermatitis.
|
23042114 |
2012 |
|
Childhood asthma
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Variants of C11orf30 were associated with the risk of childhood asthma in the Chinese population.
|
31812328 |
2019 |
|
Dermatitis, Atopic
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Variants in a locus near chromosome 11 open reading frame 30 (C11orf30) and leucine-rich repeat containing 32 (LRRC32), which was previously associated with atopic dermatitis and eczema, were also strongly associated with both phenotypes (rs2155219; P(grass) = 9.4 × 10(-9); P(AR) = 3.8 × 10(-8)).
|
22036096 |
2011 |
|
Eczema
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Variants in a locus near chromosome 11 open reading frame 30 (C11orf30) and leucine-rich repeat containing 32 (LRRC32), which was previously associated with atopic dermatitis and eczema, were also strongly associated with both phenotypes (rs2155219; P(grass) = 9.4 × 10(-9); P(AR) = 3.8 × 10(-8)).
|
22036096 |
2011 |
|
Dermatitis and eczema
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Variants in a locus near chromosome 11 open reading frame 30 (C11orf30) and leucine-rich repeat containing 32 (LRRC32), which was previously associated with atopic dermatitis and eczema, were also strongly associated with both phenotypes (rs2155219; P(grass) = 9.4 × 10(-9); P(AR) = 3.8 × 10(-8)).
|
22036096 |
2011 |
|
Crohn Disease
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Three CD susceptibility loci were independently associated with surgery within 5 years (IL12B, IL23R, and C11orf30).
|
23665963 |
2013 |
|
Malignant neoplasm of breast
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
These results support the hypothesis that EMSY overexpression can play a role in the genesis of human breast cancer.
|
16145051 |
2005 |
|
Breast Carcinoma
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
These results support the hypothesis that EMSY overexpression can play a role in the genesis of human breast cancer.
|
16145051 |
2005 |
|
Carcinoma, Ovarian Epithelial
|
0.080 |
Biomarker
|
disease |
BEFREE |
These findings support the role of EMSY as a key oncogene within the 11q13 amplicon in ovarian cancer.
|
16236351 |
2006 |
|
ovarian neoplasm
|
0.070 |
Biomarker
|
disease |
BEFREE |
These findings support the role of EMSY as a key oncogene within the 11q13 amplicon in ovarian cancer.
|
16236351 |
2006 |
|
Malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
There is no report in the literature investigating the EMSY gene in lung cancer.
|
28824300 |
2017 |
|
Carcinoma of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
There is no report in the literature investigating the EMSY gene in lung cancer.
|
28824300 |
2017 |